Products

Products

Introduction

Calorimetry is a universal detection system since heat is either generated or absorbed in every chemical process.  Calorimetry measures heat changes in enthalpy (∆H), and is the only method that directly measures heat changes associated with intra- and intermolecular interactions.  Native materials are used in the solution conditions of choice, and there is no need to chemically modify or immobilize ligands or macromolecules. 

Ultrasensitive biocalorimetry provides fundamental information on thermodynamics, which can be utilized to elucidate the structure and function of proteins, nucleic acids, lipids, drugs and other biomolecules.  This information helps scientists understand how biomolecules function, and why they are stable.  Calorimetry data can also be used to design new drugs, or to engineer proteins of higher stability or modified function.
 
The MicroCal line of Isothermal Titration Calorimetry (ITC) and Differential Scanning Calorimetry (DSC) instruments are the most sensitive, innovative and advanced in the field of ultrasensitive biocalorimetry.  These systems are designed and optimized for analysis of biomolecules in solution and are widely used at major pharmaceutical, biotech, academic and government institutions worldwide. 

The iTC₂₀₀, Auto-iTC₂₀₀, VP-ITC, VP-DSC and VP-Capillary DSC represent major advances in sensitivity, throughput, reproducibility, stability, and ease of use.  This translates into smaller sample requirements, greater precision, minimal use of bench space and the ability to generate high quality data in less time with less effort and without the need for expertise in thermodynamics.

In addition to our instrumentation line, MicroCal also offers Software and Accessories for our systems and a variety of Services.

Need more information? Contact us.