ITC
Products
Pressure Perturbation Calorimetry (PPC) Accessory
Pressure Perturbation Calorimetry (PPC) measures differential heat change (∆Q) in a biopolymer solution when the pressure above the solution is changed. The differential heat change is used to calculate volumetric properties of biopolymers in solution. PPC expands the capability of Differential Scanning Calorimetry (DSC) to include information on macromolecular salvation, accessible surface area and solvent structure.
Measurements are made possible by the addition of the PPC Accessory to a standard MicroCal VP-DSC. Special software allows studies at multiple temperatures with no operator involvement.
Applications include:
- Coefficients of thermal expansion (α).
- Volumetric properties of proteins in solvents.
- Volumetric changes of lipid bilayers.
- Volumetric changes associated with binding.
- Volumetric changes of polymers in solution.
The PPC accessory is covered under U.S. patent # 6,485,173.
PPC Reference List
Need more information? Contact us.
